Sadly I'm almost manically obsessed with LotR: The Third Age. If they could make more of that one I'd be all over it, but I think the general demand for LotR has died down. So, little hope there.
Most of the ones I was really looking forward to have come out:
L4D One and two
Fallout
Ghostbusters
Arkham Asylum
Mostly I really wish game designers could take all their fancy new CGI capabilities and use them to revamp some of the really fun old games, like Resident Evil and Parasite Eve. The original games were and still are some of the most fun I've played, and yet, to see them redone in better graphics, make the playability a little more fluid. It would be tre awesome!
So, yeah, my two cents...from a gamer chick who hasn't beaten a game successfully since Sonic the Hedgehog was on Sega Genesis...